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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INPP5D
All Species:
7.88
Human Site:
Y187
Identified Species:
17.33
UniProt:
Q92835
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92835
NP_001017915.1
1189
133292
Y187
H
L
K
A
I
Q
D
Y
L
S
T
Q
L
A
Q
Chimpanzee
Pan troglodytes
XP_526066
929
104074
Rhesus Macaque
Macaca mulatta
XP_001114794
1258
138636
H203
A
V
R
G
G
A
S
H
L
P
H
L
T
R
T
Dog
Lupus familis
XP_542327
1264
138869
N208
A
V
R
G
G
A
S
N
L
P
H
L
T
R
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES52
1191
133524
Y190
H
L
K
A
I
Q
D
Y
L
S
T
Q
L
L
L
Rat
Rattus norvegicus
P97573
1190
133575
Y189
H
L
K
A
I
Q
D
Y
L
S
T
Q
L
M
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520934
1019
113512
V50
C
V
L
Y
H
N
C
V
Y
T
Y
R
I
L
P
Chicken
Gallus gallus
XP_422567
1182
133482
L187
L
K
L
I
Q
D
Y
L
R
V
H
I
I
S
D
Frog
Xenopus laevis
Q6P4S2
1019
115278
V50
C
V
L
N
Q
N
C
V
H
T
Y
R
I
L
Q
Zebra Danio
Brachydanio rerio
Q2I6J1
1266
140353
L197
P
H
L
N
K
T
L
L
S
S
C
K
R
L
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789838
1327
148052
P189
C
L
F
D
V
Q
L
P
S
N
K
K
F
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.8
41.3
40.9
N.A.
87.8
87.8
N.A.
38.7
68.2
56.5
43.1
N.A.
N.A.
N.A.
N.A.
31
Protein Similarity:
100
77.8
57.5
56.8
N.A.
92.1
92
N.A.
48.5
78.7
67.1
57.9
N.A.
N.A.
N.A.
N.A.
47.3
P-Site Identity:
100
0
6.6
6.6
N.A.
86.6
86.6
N.A.
0
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
26.6
20
N.A.
86.6
86.6
N.A.
26.6
13.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
28
0
19
0
0
0
0
0
0
0
10
0
% A
% Cys:
28
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
10
0
10
28
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
19
19
0
0
0
0
0
0
0
0
0
0
% G
% His:
28
10
0
0
10
0
0
10
10
0
28
0
0
0
10
% H
% Ile:
0
0
0
10
28
0
0
0
0
0
0
10
28
0
0
% I
% Lys:
0
10
28
0
10
0
0
0
0
0
10
19
0
0
0
% K
% Leu:
10
37
37
0
0
0
19
19
46
0
0
19
28
37
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
19
0
19
0
10
0
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
10
0
19
0
0
0
0
10
% P
% Gln:
0
0
0
0
19
37
0
0
0
0
0
28
0
0
19
% Q
% Arg:
0
0
19
0
0
0
0
0
10
0
0
19
10
19
0
% R
% Ser:
0
0
0
0
0
0
19
0
19
37
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
0
0
19
28
0
19
10
19
% T
% Val:
0
37
0
0
10
0
0
19
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
28
10
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _